Title: Antibacterial peptides derived from Boletellus obscurecoccineus
Media summary: Staphylococcus aureus and Pseudomonas aeruginosa are the most commonly reported bacterial infections in Australian hospitals, and reports of bacterial resistance to conventional antibiotics are increasing worldwide. A new project aims to determine the specific effects and molecular mechanism of nonribosomal peptides on bacterial division. Investigations of Boletellus obscurecoccineus have found nonribosomal peptides with antibacterial properties.
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Title: New antibacterials from fungi
Media summary: Drug-resistant bacteria are a serious and increasing health problem – more than 20% of infections in Australian hospitals are resistant to conventional antibiotics. This project aims to deliver a new, highly effective treatment for these infections. The project is investigating chemicals derived from an Australian fungus – Boletellus obscurecoccineus – that have been shown to stop bacterial growth. These chemicals could be used as the basis of a treatment for a range of life-threatening infections.
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